Needle-free injection system is an innovative way to introduce medication into a patient’s body. Unlike the conventional needle injection system, needle-free injection do not penetrate through the skin. Needle-free injection system is steadily emerging as an efficient way to administer the medication with better patient compliance. There are various advantages offered by needle-free injection system. This system offers efficiency in administration of medication with better patient compliance especially for children (vaccination), geriatric patients (palliative and other care), and patients with chronic diseases such as diabetes, GI tract disease, and multiple sclerosis who need daily injection administration.
Self-medication becomes convenient with needle-free injection due to increased confidence amongst user for self-medication and therefore it offers better treatment adherence and improved quality of life. Needle-free injection eliminates needle phobia, as medication is administered through system such as jet injection system to the skin. Moreover, needle-free injection system allows drug delivery of even viscous drug, which is difficult with conventional needle syringe system.
Needle-free injection system also allows efficient delivery of biological drugs, which are unstable due to risk of protein denaturation. This is possible as needle-free injection system maintains biological integrity and it does not have silicon oil or tungsten material in its primary container. It is reusable and delivers drug faster, as compared to conventional needle syringe system due to hair size jet stream through which drug is administered.
Needle-free injection system is continuously expanding its market footprint on account of various factors. Increasing incidence of needle associated injuries and needle phobia amongst children and adults is expected to drive growth of needle-free injection system market. According to a study published in Behavioral Neurology, 2014, around 3-4 % of the world population faces needle phobia. This impacts their hospital or clinic visits, as they avoid visiting such facilities due to fear of exposure to needles. Needle phobia also impacts the vaccination amongst children, as most of them perceives injecting vaccine as a painful procedure. According to a study published in the Clinical Journal of Pain in 2015, there were 12 billion vaccination every year worldwide, most of which required injecting drug with a needle syringe system. Increasing demand for vaccines and other biologic products is another factor boosting growth of the needle-free injection system market.
According to the World Health Organization (WHO) 2018, globally around 86% of infants are vaccinated against 26 diseases, however, 19.5 million children are unvaccinated leading to death of 2-3 million children every year. Chronic disease such as diabetes often needs daily dose of insulin, which has to be administered through pain needles. This may lead to lack of adherence to treatment due to lack of confidence to self-inject insulin. Increasing research on biologics and biosimilar is another factor expected to fuel growth of the market. Biologicals are increasingly launched and prescribed to treat disease such as GI tract disease (ulcerative colitis and Crohn’s disease), central nervous system associated disease (multiple sclerosis and Alzheimer’s disease), and cancer. Other factors such as increasing incidence of communicable diseases caused due to conventional needle, increasing geriatric population worldwide who need palliative care, and growing awareness about safe injection practices are also expected to drive growth of needle-free injection system market.
Some of the key players operating in the market include Antares Pharma, Inc., Endo International plc, Portal Instruments, Inc., Zogenix, PharmaJet, Bioject Medical Technologies Inc., Medical International Technology, Inc., PenJet Corporation, INJEX Pharma AG, National Medical Products Inc., Valeritas, Inc., European Pharma Group, and Crossject SA.
Collaborations amongst companies to develop the needle-free injection system would also boost growth of needle-free injection system market. For instance, in November 2017, Takeda Pharmaceutical and Portal Instruments entered into collaboration agreement to develop the needle-free drug delivery device with the Takeda Pharmaceuticals biologic medicines for hepatitis, Crohn’s disease etc.
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